Ανακοίνωση - Πρόσκληση

Το Δι-Ιδρυματικό Μεταπτυχιακό Πρόγραμμα Σπουδών 

(ΔΠΜΣ Τμήματος Χημείας και Ινστιτούτου Βιοεπιστημών & Εφαρμογών ΕΚΕΦΕ “Δημόκριτος”)

Εφαρμοσμένη Βιοχημεία:

Κλινική Χημεία, Βιοτεχνολογία & Αξιολόγηση Φαρμακευτικών Προϊόντων

στο πλαίσιο του

"Κύκλου σεμιναρίων προσκεκλημένων ομιλητών"

που διοργανώνει

την Πέμπτη 20 Ιανουαρίου 2022 και ώρα 13:00

σας προσκαλεί στη διαδικτυακή διάλεξη της

Dr. Maria dM. Vivanco

CIC bioGUNE, Spain

on the subject:

Breast cancer heterogeneity and resistance to therapy

σε σύνδεση μέσω zoom:

https://upatras-gr.zoom.us/j/5583501511?pwd=M2cyNjdWMFdQeEFjSVpsb1NZWDgzQT09 

________________________________________

Announcement - Invitation

The Postgraduate Program

(Joint Postgraduate Programme of the Department of Chemistry and the Institute of Biosciences and Applications of NCSR "Demokritos”)

Applied Biochemistry:

Clinical Chemistry, Biotechnology & Evaluation of Pharmaceutical Products

 in the context of

"Seminars of invited speakers"

invites you to her online lecture on

Thursday, January 20, 2022 at 12:00 CET

Dr. Maria dM. Vivanco

CIC bioGUNE, Spain

on the subject:

Breast cancer heterogeneity and resistance to therapy

online zoom:

https://upatras-gr.zoom.us/j/5583501511?pwd=M2cyNjdWMFdQeEFjSVpsb1NZWDgzQT09  

______________________________________________________

Short cv: María dM. Vivanco graduated from the University of the Basque Country, worked at Sandoz (Basel) and carried out her PhD thesis at EMBL (Heidelberg). After her post-doctoral studies at UCSF (San Francisco), María started her own lab at the Institute of Cancer Research in London, where she identified mammary stem/progenitor cells in the human breast. At CIC bioGUNE, her team is characterising normal and cancer stem cells and examining their role in resistance to endocrine therapy. She is on the committee of the European Network for Breast Development and Cancer and has worked with breast cancer charities, including Breakthrough (UK) and Acambi (Spain).

Short talk description: Breast cancer is the most frequently diagnosed cancer and the leading cause of death from cancer in women worldwide. Breast cancer is a heterogeneous disease. Cancer cells cannot function in isolation: tumours are populated by epithelial cells, stromal cells and immune cells, as well as small populations of normal stem cells and cancer stem cells (CSCs). In particular, the presence of CSCs proves a challenge to therapy and their identification and characterisation in breast cancer has opened new possibilities for anti-cancer therapies. CSCs are implicated in tumour initiation and resistance to current treatments, including endocrine therapy. We have previously shown that increase of CSC content during development of resistance to tamoxifen in breast cancer is driven by multiple signals, including Sox2-dependent activation of Wnt signalling. These findings highlight the relevance of Sox family transcription factors as potential therapeutic targets in breast cancer.

Ανακοίνωση - Πρόσκληση

Το Δι-Ιδρυματικό Μεταπτυχιακό Πρόγραμμα Σπουδών 

(ΔΠΜΣ Τμήματος Χημείας και Ινστιτούτου Βιοεπιστημών & Εφαρμογών ΕΚΕΦΕ “Δημόκριτος”)

Εφαρμοσμένη Βιοχημεία:

Κλινική Χημεία, Βιοτεχνολογία & Αξιολόγηση Φαρμακευτικών Προϊόντων

στο πλαίσιο του

"Κύκλου σεμιναρίων προσκεκλημένων ομιλητών"

που διοργανώνει

την Πέμπτη 13 Ιανουαρίου 2022 και ώρα 13:00

σας προσκαλεί στη διαδικτυακή διάλεξη της

Prof. Patricia ROUSSELLE

CNRS, Lyon, France

με θέμα:

Cell / microenvironment cross talk and tissue repair 

σε σύνδεση μέσω zoom:

https://upatras-gr.zoom.us/j/5583501511?pwd=M2cyNjdWMFdQeEFjSVpsb1NZWDgzQT09 

________________________________________

Announcement - Invitation

The Postgraduate Program

(Joint Postgraduate Programme of the Department of Chemistry and the Institute of Biosciences and Applications of NCSR "Demokritos”)

Applied Biochemistry:

Clinical Chemistry, Biotechnology & Evaluation of Pharmaceutical Products

 in the context of

"Seminars of invited speakers"

invites you to her online lecture on

Thursday, January 13, 2022 at 12:00 CET

Prof. Patricia ROUSSELLE

CNRS, Lyon, France

on the subject:

Cell / microenvironment cross talk and tissue repair 

online zoom:

https://upatras-gr.zoom.us/j/5583501511?pwd=M2cyNjdWMFdQeEFjSVpsb1NZWDgzQT09  


Short cv: Prof Patricia Rousselle is research director at the National Centre for Scientific Research (CNRS) in France and her research is focused on understanding cell / extracellular matrix interactions in the context of skin biology. Developing both biochemical and cell biology approaches, her group is interested in analyzing molecular and cellular events occurring during wound repair, focusing on cell adhesion, migration processes governed by extracellular glycoproteins and proteoglycans. Her recent work has focused on the interactions of basal keratinocytes with extracellular matrix components during the re-epithelialisation phase of wound repair. She is currently past president of the French Society for Matrix Biology, and she is a member of the board of Directors of the European Tissue Repair Society (ETRS). Patricia Rousselle obtained a doctorate in Pharmacy in 1988 and pursued a four-year residency in clinical biology at Lyon University-Hospitals, where she also gained an MSc in Molecular and Cellular Biology in 1990. She started a doctoral training at the Shriners Hospital for Crippled Children in Portland, USA, where she discovered the important dermal epidermal junction protein laminin 332. She thereafter worked at the Cutaneous Biology Research Center in Boston, USA, before she joined the French CNRS in 1995 to set up her own group. Since then, she conducts her research team independently through research funding, partnerships with industry and scientific collaborations.

Short talk description: The formation of complex organs, the organization of cells within them, and the expression of tissue-specific genes require a combination of spatial instructions from the extracellular matrix and intercellular adhesions, together with temporal signals from soluble factors such as growth factors), hormones and cytokines. The precise integration of the resulting intracellular signaling networks drives the principal cellular processes of suppression of apoptosis, cell cycle, migration and differentiation, which are all key to the morphogenesis and function of tissues.


Nikos Karamanos, PhD, ERT

Professor of Biochemistry I Dept. of Chemistry, University of Patras, GR
E-mail: 

Πρόσκληση σε Διαδικτυακή Συνάντηση Επιστήμης

Η καινοτόμος δύναμη της Χημείας στην αντιμετώπιση των προκλήσεων του μέλλοντος

Ίδρυμα Ευγενίδου (www.eef.edu.gr)

21 Δεκεμβρίου 2021, 6-8 μμ

-----------------------------------------------

Θα θέλαμε να σας προσκαλέσουμε να συμμετάσχετε στη διαδικτυακή συνάντηση με τίτλο: «Η καινοτόμος δύναμη της Χημείας στην αντιμετώπιση των προκλήσεων του μέλλοντος», η οποία προγραμματίζεται να πραγματοποιηθεί την Τρίτη 21 Δεκεμβρίου και ώρα 18:00.

Η εκδήλωση εντάσσεται στο πλαίσιο των «Συναντήσεων Επιστήμης» που διοργανώνεται από το Ίδρυμα Ευγενίδου (www.eef.edu.gr) για τις Θετικές Επιστήμες (https://www.eef.edu.gr/el/to-idryma/online-draseis/synantiseis-epistimis/.και πλαισιώνεται από κορυφαίους επιστήμονες και μέλη της ακαδημαϊκής κοινότητας, ανάμεσα στους οποίους και δύο έγκριτα μέλη της Σχολής Θετικών Επιστημών του Πανεπιστημίου Πατρών, οι κ.κ. Νίκος Καραμάνος και Χρήστος Κορδούλης, Καθηγητές του Τμήματος Χημείας.

Συμμετέχει επίσης και ο Ιωάννης Παπαεσταθίου, Καθηγητής του Τμήματος Χημείας του ΕΚΠΑ.

Τη συζήτηση θα συντονίσει ο Γεώργιος Δάσιος, Ομότιμος Καθηγητής των Εφαρμοσμένων Μαθηματικών στο Πανεπιστήμιο Πατρών και αντεπιστέλλον μέλος της Ακαδημίας Αθηνών.

Συγκεκριμένα:
1.    ο κ. Νίκος Καραμάνος θα συντονίσει τη συνάντηση και θα εισηγηθεί σχετικά με τον «Κομβικό ρόλο της Χημείας στις μελλοντικές προκλήσεις της ανθρωπότητας»,
2.    ο κ. Χρήστος Κορδούλης θα επικεντρωθεί στην ομιλία του για τη «Χημεία ως πυλώνα βιώσιμης ανάπτυξης», ενώ
3.    ο κ. Ιωάννης Παπαευσταθίου θα μιλήσει για τη «Χημεία στην αντιμετώπιση των προκλήσεων του νερού».


Το θέμα της συνάντησης έχει σημαντικό διαθεματικό ενδιαφέρον μιας και η Χημεία αποτελεί τη βάση της ζωής και της φύσης. Είναι η επιστήμη που διασφαλίζει ότι έχουμε φάρμακα για την πρόληψη και τη θεραπεία των ασθενειών, επαρκή τρόφιμα τα οποία είναι ασφαλή,  προϊόντα προσωπικής φροντίδας και υγιεινής και τόσα άλλα.

 Όλα μέρη του κόσμου θα βιώσουν τις μεγάλες τάσεις που δημιουργούνται από τις προκλήσεις του μέλλοντος, λόγω της αύξησης του πληθυσμού, της κατανάλωσης των πόρων, και των ασθενειών. Το ερώτημα πως η Χημεία θα αντιμετωπίσει τις μελλοντικές επιπτώσεις είναι επίκαιρο και επιτακτικό. Στην επιστημονική αυτή συνάντηση θα συζητηθούν σημαντικές προκλήσεις για το μέλλον στις οποίες η Χημεία μπορεί να διαδραματίσει κομβικό ρόλο.

Πληροφορίες για την εγγραφή στην διαδικτυακή συζήτηση των «Συναντήσεων Επιστήμης» ή για να παρακολουθήσετε το κανάλι του Ιδρύματος Ευγενίδου στο YouTube δίνονται:https://www.eef.edu.gr/el/to-idryma/online-draseis/synantiseis-epistimis/i-kainotomos-dynami-tis-himeias-stin-antimetopisi-ton-prokliseon-tou-mellontos/

---------------------------------
Γεώργιος Παπαθεοδώρου
Κοσμήτορας Σχολής Θετικών Επιστημών
Πανεπιστήμιο Πατρών
26504 Πάτρα

Τηλ. 2610 969638 - 2610 996275
email: nsdean@upatras.g

Το Δι-Ιδρυματικό Μεταπτυχιακό Πρόγραμμα Σπουδών 

(ΔΠΜΣ Τμήματος Χημείας και Ινστιτούτου Βιοεπιστημών & Εφαρμογών ΕΚΕΦΕ “Δημόκριτος”)

Εφαρμοσμένη Βιοχημεία:

Κλινική Χημεία, Βιοτεχνολογία & Αξιολόγηση Φαρμακευτικών Προϊόντων

στο πλαίσιο του

"Κύκλου σεμιναρίων προσκεκλημένων ομιλητών"

που διοργανώνει

την Τετάρτη 22 Δεκεμβρίου 2021 και ώρα 13:00

σας προσκαλεί στη διαδικτυακή διάλεξη του

Prof. Martin Götte

Münster University Hospital, Münster, Germany

με θέμα:

Role of Cell Surface Heparan Sulfate Proteoglycans in Cancer and Inflammation

σε σύνδεση μέσω zoom:

https://upatras-gr.zoom.us/j/5583501511?pwd=M2cyNjdWMFdQeEFjSVpsb1NZWDgzQT09

________________________________________

Announcement - Invitation

The Postgraduate Program

(Joint Postgraduate Programme of the Department of Chemistry and the Institute of Biosciences and Applications of NCSR "Demokritos”)

Applied Biochemistry:

Clinical Chemistry, Biotechnology & Evaluation of Pharmaceutical Products

 in the context of

"Seminars of invited speakers"

invites you to his online lecture on

Wednesday, December 22, 2021 at 13:00

Prof. Martin Götte

Münster University Hospital, Münster, Germany

on the subject:

Role of Cell Surface Heparan Sulfate Proteoglycans in Cancer and Inflammation

online zoom:

https://upatras-gr.zoom.us/j/5583501511?pwd=M2cyNjdWMFdQeEFjSVpsb1NZWDgzQT09

______________________________________________________

Short cv: Martin Götte is  a  Professor  at  the Department  of  Gynecology and  Obstetrics of the  University of Münster, Germany.  He obtained his diploma (Biology) in 1994 at the University of Münster, and his Ph.D.  (Biochemistry) in 1997 from the University of Göttingen and the Max-Planck-Institute for Biophysical Chemistry. After postdoctoral   research at the Department of Cell Biology of Harvard Medical School, Boston, USA, he obtained a tenured position as head of the research laboratory of the Department of Gynecology and Obstetrics of Münster University Hospital. His main areas of research are the role of syndecans, decorin, and glycosaminoglycan biosynthetic enzymes in cancer and inflammation. 

Short talk description: The malignant behavior of cancer cells is determined not only by cell-autonomous factors but also by a permissive microenvironment. The extracellular matrix (ECM) plays a major role in either supporting or inhibiting tumor cell behavior. Epigenetic mechanisms and a dysregulated endocrine milieu favor altered ECM synthesis. Aberrant production and function of cell surface proteoglycans conveys signals to tumor which promote metastatic behavior, unlimited tumor growth, and cancer stem cell function linked to therapeutic resistance and relapse. Proteoglycans mediate matrix-dependent signaling events via growth factors and chemokines, modulating angiogenesis and immune cell function in the tumor microenvironment. Moreover, they regulate the function of immune cells, shifting their function from an anti-cancerous to a permissive state. Focusing on the function of the cell surface proteoglycan family of syndecans, this lecture will provide basic knowledge on the function of these proteoglycans in signal transduction, matrix adhesion and degradation, and in regulating inflammatory processes and angiogenesis in the context of tumor progression.

__________________

Prof. Nikos Karamanos

Αγαπητά μέλη του Τμήματος Χημείας,

Την Δευτέρα 7 Ιουνίου, ώρα 5 μμ, θα πραγματοποιηθεί τηλεδιάλεξη με προσκεκλημένο ομιλητή τον Dr. Andrea Carfi, Vice-President of Moderna & Head of Research for Infectious Disease.

ΘΕΜΑ: “Development of Moderna COVID-19 vaccine and preparing for variants of concern”

Η τηλεδιάλεξη  πραγματοποιείται στο πλαίσιο του μεταπτυχιακού προγράμματος ‘Αναλυτική Χημεία & Νανοτεχνολογία’ και απευθύνεται σε ευρύ ακροατήριο.

Σύνδεσμος:

https://upatras-gr.zoom.us/j/96020984114?pwd=ZTJuaFRtdTRGOW9aaC9FbmJralZTUT09
Meeting ID: 960 2098 4114
Passcode: 254846


Σύντομο βιογραφικό του ομιλητή.

Dr. Andrea Carfi holds a Master of Science in Physics from University of Canterbury in UK, Laura degree (equivalent to Master of Science in Chemistry) from Pavia University, Italy, and a PhD in Biophysics from the Université Joseph Fourier in Grenoble, France. He was also trained as a postdoctoral fellow in the laboratories of Prof. Stephen Harrison and Prof. Don Wiley at Boston Children’s Hospital/Harvard. Dr. Carfi has more than 18 years of experience in drug discovery and vaccine development at Moderna, GSK, Novartis Vaccines and IRBM/Merck. Over the years he has covered roles of increasing responsibility with a focus on structural biology, antigen design, small molecule antivirals discovery and vaccines development. In particular, during the seven years at GSK and Novartis Vaccines, he led the US based Protein Biochemistry team and was responsible for the design, selection, characterization and early development of novel vaccines against infectious disease targets, including HIV, CMV and RSV. Some of these vaccine candidates are now in early and late stage clinical trials. He was also heading the Novartis Vaccines Antigen Design platform across the research sites of Cambridge, US and Siena, Italy. Dr. Carfi joined Moderna in 2017 as Sr. Director of Antigen Design and Selection and Project Leader for the CMV vaccine program now in a Phase 1 clinical trial. Dr. Carfi has become the Head of Research for Infectious Disease since January 2019 and he is currently leading Research for all Moderna Infectious Disease targets.


Με εκτίμηση

Θεόδωρος Χριστόπουλος
Καθηγητής
Τμήμα Χημείας
Πανεπιστήμιο Πατρών
& σμΔΕΠ ΙΕΧΜΗ/ΙΤΕ

Αγαπητοί χαίρετε,

Αύριο, Τρίτη 11 Μαΐου, ώρα 6:30 μμ, θα πραγματοποιηθεί τηλεδιάλεξη με θέμα:

“Artificial Intelligence in Drug Discovery: What is Realistic, What are Illusions?”

Προσκεκλημένος ομιλητής: Andreas Bender, Reader, Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Cambridge, UK

Η τηλεδιάλεξη  πραγματοποιείται στο πλαίσιο του μεταπτυχιακού προγράμματος ‘Αναλυτική Χημεία & Νανοτεχνολογία’, καλύπτει διεπιστημονική ερευνητική δραστηριότητα και απευθύνεται σε ευρύ ακροατήριο.

Σύνδεσμος:
https://upatras-gr.zoom.us/j/96020984114?pwd=ZTJuaFRtdTRGOW9aaC9FbmJralZTUT09
Meeting ID: 960 2098 4114
Passcode: 254846

Ακολουθεί η περίληψη της διάλεξης και σύντομο βιογραφικό του ομιλητή.

Abstract: Artificial Intelligence (AI) has had a profound impact on areas such as image and speech recognition; however, comparable advances in drug discovery are still rare. This contribution will explore some of the reasons why this is the case, starting firstly by embedding the application of AI in drug discovery into its historical context. Next, we will explore which types of improvements – namely to speed, cost, or quality of decisions – are able to have the most profound impact on the success of drug discovery projects, and we will see that it is quality of decisions in clinical phases that matters most for project success. However, while computational algorithms are tremendously powerful today, much of the data we have available in drug discovery projects comes from the preclinical, proxy domain – which possesses only limited utility to make predictions for clinical stages. Hence, while numerically we are at least to an extent becoming better at modelling proxy endpoints, this leads to a ‘models of models’ situation, which only translates to a very limited extent to the safety and efficacy of compounds which will reach patients in a clinical setting. Even more fundamentally, there are intrinsic aspects of chemical and biological data which make labelling data much more difficult than in the image- or speech-domain, such as its conditionality (e.g. the dependence of effects on dose), which pose conceptual problems to being able to apply computational algorithms in the drug discovery domain. The contribution will conclude with aspects of model validation and perceptions of AI in society which pose additional problems for their unbiased evaluation and development, and point out developments which are needed for applications of AI in drug discovery to contribute to the clinical safety and efficacy of future medicines.

--Andreas Bender and Isidro Cortés-Ciriano. Artificial intelligence in drug discovery: what is realistic, what are illusions? Part 1: Ways to make an impact, and why we are not there yet. Drug Discovery Today, 2021 (26) 2, 511 – 524.
--Andreas Bender and Isidro Cortes-Ciriano. Artificial intelligence in drug discovery: what is realistic, what are illusions? Part 2: a discussion of chemical and biological data. Drug Discovery Today, 2021 (in press, DOI: 10.1016/j.drudis.2020.11.037).


Short CV:
Dr Andreas Bender is Director for Digital Life Sciences at Nuvisan in Berlin, as well as a Reader for Molecular Informatics with the Centre for Molecular Science Informatics at the Department of Chemistry of the University of Cambridge. In his work, Andreas is involved with the integration and analysis of chemical and biological data from different sources, such as structural and bioactivity data, gene expression readouts, cellular imaging data, pathway information, etc. The computational analysis of this information is in his research then aimed at understanding phenotypic compound action – such as cellular readouts and organism-level effects – on a mechanistic level, predicting molecular properties related to both compound effiacy and toxicity, as well as e.g. compound repurposing. He received his PhD from the University of Cambridge and worked in the Lead Discovery Informatics group at Novartis in Cambridge/MA as well as at Leiden University in the Netherlands and at AstraZeneca before his current post.


Με εκτίμηση

Θεόδωρος Χριστόπουλος
Καθηγητής
Τμήμα Χημείας

Αγαπητοί φοιτητές,
 
Την  Πέμπτη, 15 Απριλίου, ώρα 8:00 μμ, θα πραγματοποιηθεί τηλεδιάλεξη με θέμα:
 
“Multispectral Imaging of Cultural Heritage: Methods and Results”
 
Προσκεκλημένος ομιλητής: Roger L. Easton, Jr., Professor, Chester F. Carlson Center for Imaging Science, Rochester Institute of Technology, Rochester, NY
 
Η τηλεδιάλεξη  πραγματοποιείται στο πλαίσιο του μεταπτυχιακού προγράμματος ‘Αναλυτική Χημεία & Νανοτεχνολογία’ με την υποστήριξη του Εργαστηρίου Παλαιογραφίας του Τμήματος Φιλολογίας. Καλύπτει διεπιστημονική ερευνητική δραστηριότητα και απευθύνεται σε ευρύ ακροατήριο.
 
Σύνδεσμος:
https://upatras-gr.zoom.us/j/96020984114?pwd=ZTJuaFRtdTRGOW9aaC9FbmJralZTUT09
Meeting ID: 960 2098 4114
Passcode: 254846
 
Ακολουθεί περίληψη της διάλεξης και σύντομο βιογραφικό του ομιλητή.
 
Abstract
Imaging systems, illumination tools, and processing methods newly developed in the last 2-3 decades have dramatically improved recovery of text and other features from manuscripts. As a result, heretofore unreadable (or even unknown) texts may be recovered, which promises a possible new age of scholarship in cultural heritage. Among the objects that have been studied using such emerging methods include manuscripts that were deliberately erased and overwritten to form "palimpsests," including manuscripts with erased writings by Archimedes, Galen, and Dexippus. In another example, faded text was recovered from the c. 1491 map of the world by Henricus Martellus Germanus. This talk will review new imaging equipment, including illumination, lenses, and sensors, as well as processing methods that have been applied to the imagery of these objects. Long-range plans for wide dissemination of equipment and expertise will be described.
 
Short CV
Roger L. Easton, Jr. has been on the faculty of the Chester F. Carlson Center for Imaging Science since 1986. During that time, his research interests evolved from optical signal processing and holography to the application of modern imaging technologies to recovery of writings from cultural heritage. He led the imaging team for the project to recover erased text from the Archimedes palimpsest, which led to discoveries of writings by Hypereides and a commentary on Aristotle's "Categories." He was also on teams to image the Syriac-Galen, Dexippus, Jubilees, Zacynthius, and Herodian palimpsests and the palimpsests in the "New Finds" at St. Catherine's Monastery, as well as maps of the world by Henricus Martellus Germanus (c. 1491) and Martin Waldseemüller (1507).

Οι διοργανωτές
 
Θεόδωρος Χριστόπουλος, Καθηγητής, Τμήμα Χημείας
Φεβρωνία Νούσια, Επίκουρη Καθηγήτρια, Τμήμα Φιλολογίας

Αγαπητά μέλη της πανεπιστημιακής κοινότητας,

Τη Δευτέρα, 12 Απριλίου, ώρα 7 μμ, θα πραγματοποιηθεί τηλεδιάλεξη με θέμα:

“DNA Computing for DNA Data Storage and Disease Diagnosis”

Προσκεκλημένος ομιλητής: Georg Seelig, Professor in Electrical & Computer Engineering and the Paul G. Allen School for Computer Science & Engineering at the University of Washington.

Η τηλεδιάλεξη  πραγματοποιείται στο πλαίσιο του μεταπτυχιακού προγράμματος ‘Αναλυτική Χημεία & Νανοτεχνολογία’, καλύπτει διεπιστημονική ερευνητική δραστηριότητα και απευθύνεται σε ευρύ ακροατήριο.

Σύνδεσμος:
https://upatras-gr.zoom.us/j/96020984114?pwd=ZTJuaFRtdTRGOW9aaC9FbmJralZTUT09
Meeting ID: 960 2098 4114
Passcode: 254846

Ακολουθεί περίληψη της διάλεξης και σύντομο βιογραφικό του ομιλητή.

Abstract: In this talk, I will briefly introduce the field of DNA computing starting with work by Adleman. I will then highlight two different applications for DNA computing. First, I will introduce a molecular computation for disease diagnosis. Our workflow begins by training a computational classifier on labelled gene expression data. This in silico classifier is then realized at the molecular level to enable expression analysis and classification of previously uncharacterized RNA samples. Classification occurs through a series of molecular interactions between RNA inputs and engineered DNA probes designed to differentially weigh each input according to its importance. Second, I will introduce an approach for performing computation in the context of DNA data storage. Synthetic DNA has the potential to store the world's continuously growing amount of data in an extremely dense and durable medium. Current proposals for DNA-based digital storage systems include the ability to retrieve individual files by their unique identifier, but not by their content. Here, we demonstrate content-based retrieval from a DNA database by learning a mapping from images to DNA sequences such that an encoded query image will retrieve visually similar images from the database via DNA hybridization. We encoded and synthesized a database of 1.6 million images and queried it with a variety of images, showing that each query retrieves a sample of the database containing visually similar images are retrieved at a rate much greater than chance.

Short CV: Georg Seelig is a professor in Electrical & Computer Engineering and the Paul G. Allen School for Computer Science & Engineering at the University of Washington. He is an adjunct professor in Bioengineering. Seelig holds a PhD in physics from the University of Geneva in Switzerland and did postdoctoral work in synthetic biology and DNA nanotechnology at Caltech. He received a Burroughs Wellcome Foundation Career Award at the Scientific Interface in 2008, an NSF Career Award in 2010, a Sloan Research Fellowship in 2011, and a DARPA Young Faculty Award in 2012, an ONR Young Investigator Award in 2014 and a Microsoft Research Outstanding Collaborator Award in 2016.

Seelig is interested in understanding how biological organisms process information using complex biochemical networks and how such networks can be engineered to program cellular behavior. His approach combines forward engineering of synthetic RNA-based regulatory circuits with the quantitative characterization of existing RNA-based gene regulatory pathways. His group is applying engineered circuits to problems in disease diagnostics and therapy.

Με εκτίμηση

Θεόδωρος Χριστόπουλος
Καθηγητής
Τμήμα Χημείας

Ημερομηνία: Παρασκευή, 11/10/2019

Ώρα: 13.00

Αίθουσα: Σεμιναρίων Τμήματος Χημείας

ΔΙΑΛΕΞΗ

 

Lanthanides in Molecular Magnetism

Dr Júlia Mayans

Department of Chemistry, University of Barcelona, Barcelona, Spain

Lanthanide complexes represent a fascinating and challenging class of molecular magnetic materials with implications in several modern areas of fundamental and applied chemistry and physics. Due to their unique chemical and electronic properties, lanthanides have contributed to the field of molecular magnetism, and especially in the areas of molecular spintronics and quantum computation. This presentation will cover the recent advances in the field and some of our recent research results.

Ημερομηνία: Τετάρτη, 09/10/2019

Ώρα: 12.00

Αίθουσα: Σεμιναρίων Τμήματος Χημείας

ΔΙΑΛΕΞΗ

 

Supramolecular Assemblies: Structures and Magnetism

Prof. Albert Escuer

Department of Chemistry, University of Barcelona, Barcelona, Spain

Supramolecular chemistry, based on non-covalent interactions, covers a wide variety of systems that include the coordination chemistry and the properties of supramolecular coordination assemblies with interesting applications in several fields, such as sensing, molecular recognition, catalysis, to name a few. This presentation will cover an overview of supramolecular concepts, including fundamental principles and recent examples, as well as their implications in molecular magnetism.

Σας ενημερώνω ότι το πρόγραμμα διαλέξεων του Καθ. Carlos L. Cespedes Acuña, προσκεκλημένου του Τμήματος Χημείας έχει ως εξής:

Δευτέρα 03.06.19  και ώρα 10:00 π.μ.

“Inhibition on Cholinesterase and Tyrosinase by alkaloids and phenolics from Aristotelia chilensis leaves”  

Τρίτη 04.06.19  και ώρα 12:00 μ.μ.

“Biological Activities of Chilean Plants: a look at the new paradigms” 

Οι ανωτέρω διαλέξεις θα πραγματοποιηθούν στην Αίθουσα Σεμιναρίων του Τμήματος Χημείας (Ισόγειο Βορ. Κτιρίου).

Με εκτίμηση,

Κωνσταντίνος Αθανασόπουλος

Αναπλ. Καθηγητής

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Λίστες ανακοινώσεων

Οι λίστες ανακοινώσεων για το Τμήμα είναι διαθέσιμες στον παρακάτω σύνδεσμο: Λίστες ανακοινώσεων για το Τμήμα Χημείας

Έντυπα Γραμματείας

Στον παρακάτω σύνδεσμο υπάρχουν συγκεντρωμένα τα έντυπα της Γραμματείας: Έντυπα Γραμματείας

ΔΗΛΩΣΕΙΣ ΜΑΘΗΜΑΤΩΝ

ΠΑΡΑΤΑΣΗ ΔΗΛΩΣΗΣ ΧΕΙΜΕΡΙΝΩΝ ΜΑΘΗΜΑΤΩΝ ΑΚΑΔ. ΕΤΟΥΣ 2021-22
ΠΑΡΑΤΑΣΗ ΔΗΛΩΣΗΣ ΕΑΡΙΝΩΝ ΜΑΘΗΜΑΤΩΝ ΑΚΑΔ. ΕΤΟΥΣ 2021-22 ΓΙΑ ΤΟΥΣ ΕΠΙ ΠΤΥΧΙΩ
ΔΗΛΩΣΕΙΣ ΜΑΘΗΜΑΤΩΝ ΓΙΑ ΤΑ ΜΕΤΑΠΤΥΧΙΑΚΑ ΠΡΟΓΡΑΜΜAΤΑ
ΔΗΛΩΣΕΙΣ ΜΑΘΗΜΑΤΩΝ ΓΙΑ ΤΟ ΜΕΤΑΠΤΥΧΙΑΚΟ ΠΡΟΓΡΑΜΜΑ: ΔΠΜΣ «ΕΦΑΡMΟΣΜΕΝΗ ΒΙΟΧΗΜΕΙΑ: ΚΛΙΝΙΚΗ ΧΗΜΕΙΑ, ΒΙΟΤΕΧΝΟΛΟΓΙΑ, ΑΞΙΟΛΟΓΗΣΗ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΠΡΟΪΟΝΤΩΝ»
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