Professor

Tel: (+302610) 962953

e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Web Page: http://www.chem.upatras.gr/faculty/nastopoulos

List of Publications: www.webofknowledge.com

Contact hours: Tuesday and Friday 11:00-13:00

Curriculum Vitae

Education
Diploma in Chemistry, University of Patras, Greece (1979)
Licence spéciale en Sciences Chimiques, Université Catholique de Louvain, Louvain-la-Neuve, Belgium (1984)
Ph.D. in Chemistry (X-ray crystallography), University of Patras, Greece (1987)

Research training and experience
1983-1986: Département de Chimie, Université Catholique de Louvain (small-molecule X-ray crystallography, direct methods)
1986 (short-term): Department of Physics, University of York (direct methods)
1992: EMBL, Biological Structures Programme, Heidelberg (protein crystallography)
1994-2002 (short-term visits): Dipartimento di Scienze Biochimiche, Università degli Studi di Roma 'La Sapienza' (protein crystallography)

Books (educational material)
'Structural Chemistry', Department of Chemistry, University of Patras (2015)
‘Quantitative Analysis Laboratory Notes’, Department of Chemistry, University of Patras (2015)

Professional Affiliations
The Association of Greek Chemists, Hellenic Crystallographic Association, Hellenic Society of Biochemistry and Molecular Biology, Hellenic Society for Biological Sciences

Fellowships/Grants
Greek State Scholarships Foundation, education scholarship (1975-1978), Ministry of National Economy (Greece), postgraduate research fellowship (1983-1986), Erasmus grant (1990), Human Capital and Mobility research fellowship (1995), Short-term research fellowships: ΕMBL (1991, 1993), FEBS (1994), Istituto Pasteur-Fondazione Cenci Bolognetti (1996-2000)

Participation in research projects
PENED 1995 and 1999 and EPETII 1997 (Greek Secretariat for Research and Technology), C. Karatheodori 2000 and 2008 (University of Patras), PythagorasII 2004 (Greek Ministry of Education), BE-OPT/X-FEL (GSRT, 2011)

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Courses

Undergraduate program
Structural Chemistry
Analytical Chemistry II
Analytical Chemistry I and II (lab)

Postgraduate program
Analytical Chemistry and Nanotechnology (Methods in X-ray Structural Analysis)

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Research Activities

• Crystal engineering – Metallosupramolecular chemistry
• Crystal structure determination of proteins and small molecules by single-crystal x-ray crystallography
• Software development (coordination geometry of complex compounds, x-ray crystallography, etc)

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Representative Publications

• K. Kounavi, A. Kitos, E. Moushi, M. Manos, C. Papatriantafyllopoulou, A. Tasiopoulos, S. Perlepes, V. Nastopoulos.
  Supramolecular features in the engineering of 3d metal complexes with phenyl-substituted imidazoles as ligands: the case of copper(II).
  CrystEngComm., 17, 7510 (2015).
• K. Kounavi, E. Moushi, M. Manos, C. Papatriantafyllopoulou, A. Tasiopoulos, V. Nastopoulos.
  Supramolecular patterns of cationic and neutral Ni(II) complexes from the interplay of hydrogen-bonding, stacking interactions and metal-coordination motifs.
  CrystEngComm., 14, 6492 (2012).
• Moushi, C. Lampropoulos, W. Wernsdorfer, V. Nastopoulos, G. Christou, A. Tasiopoulos.
  Inducing single-molecule magnetism behavior in a family of loop-of-loops aggregates: Heterometallic Mn40Na4 clusters and the homometallic Mn44 analogue.
  Journal of the American Chemical Society, 132, 16146 (2010).
• A. Boudalis, B. Donnadieu, V. Nastopoulos, J.M. Clemente-Juan, A. Mari, Y. Sanakis, J.-P. Tuchagues & S.P. Perlepes.
  'A Nonanuclear Iron(II) Single-Molecule Magnet'.
  Angewandte Chemie International Edition, 43, 2266 (2004).
• C. Savino, L. Federici, V. Νastopoulos, K.A. Johnson, F. Pisani, M. Rossi, M. Brunori & D. Tsernoglou.
  'Structure of DNA polymerase from the archaeon Sulfolobus solfataricus'.
  Structure, 12, 2001 (2004).
• A. Ilari, K. Johnson, V. Nastopoulos, D. Verzili, C. Zamparelli, G. Colotti, D. Tsernoglou & E. Chiancone.
  'The crystal structure of the sorcin calcium binding domain provides a model of Ca²⁺-dependent processes in the full-length protein'.
  Journal of Molecular Biology, 317, 447 (2002).
• V. Nastopoulos, A. Ilari, G. Colotti, C. Zamparelli, D. Verzili, E. Chiancone & D. Tsernoglou.
  'Two different crystal forms of sorcin, a penta-EF-hand Ca²⁺-binding protein'.
  Acta Crystallographica, D57, 862 (2001).
• V. Nastopoulos, P. Kanellopoulos & D. Tsernoglou.
  'The dimeric and monomeric erabutoxin a crystal structure refined at 1.5 Å resolution'.
  Acta Crystallographica, D54, 964 (1998).
• G. Germain, V. Nastopoulos & M.M. Woolfson.
  'On the application of Phase Relationships to Complex Structures: XXIX. Choosing the Large Es'.
  Acta Crystallographica, A47, 278 (1991).